DNA Binding Motif

						

			
Accessions: E2F3_TBX21_2 (HumanTF2 1.0)

			
Names: E2F3_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: rgGTGykAwgGCGCstTsdCrcg
Weblogo: 
PSSM: P0      A      C      G      T
01     78     37     60     30      r
02     82     82    204     71      g
03     22     15    204     22      G
04      3     67      0    204      T
05      0      0    204      3      G
06     33    108     21    204      y
07     33     71    204    110      k
08    197      0      8      0      A
09     71      8     42     84      w
10     29     52    204     42      g
11      0      0    204      3      G
12      2    204      2      0      C
13      3      5    204      0      G
14      0    204     16      0      C
15     18     84    120      8      s
16     30     39     11    125      t
17      7     27      5    165      T
18     49     60     67     29      s
19     57      8     78     61      d
20      2    204      2      8      C
21     99      0    106      5      r
22     43    161     48      5      c
23     38     40     89     38      g
Type: Heterodimer
Binding TFs: TBX21_TF2 (T-box)
E2F3_TF1 (E2F/DP family winged-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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