DNA Binding Motif

						

			
Accessions: 2hzv_ABCD (3D-footprint 20231221)

			
Names: Nickel-responsive regulator
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: NikR-operator DNA complex
Length: 28
Consensus: GTyTGAnnnnnnnnnnnnnnnnTCAwAC
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      0      0      0     96      T
03      8     24      8     56      y
04      0      0      0     96      T
05      0      0     96      0      G
06     96      0      0      0      A
07     24     24     24     24      n
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12     24     24     24     24      n
13     24     24     24     24      n
14     24     24     24     24      n
15     24     24     24     24      n
16     24     24     24     24      n
17     24     24     24     24      n
18     24     24     24     24      n
19     24     24     24     24      n
20     24     24     24     24      n
21     24     24     24     24      n
22     24     24     24     24      n
23      0      0      0     96      T
24      0     96      0      0      C
25     80      0     16      0      A
26     48      8     16     24      w
27     96      0      0      0      A
28      0     96      0      0      C
Binding TFs: 2hzv_A / 2hzv_B / 2hzv_C / 2hzv_D (Ribbon-helix-helix protein, copG family, NikR C terminal nickel binding domain)
Binding Sites: 2hzv_I
2hzv_J
			
Publications: Schreiter E.R, Wang S.C, Zamble D.B, Drennan C.L. NikR-operator complex structure and the mechanism of repressor activation by metal ions. Proceedings of the National Academy of Sciences of the United States of America 103:13676-81 (2006). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.