DNA Binding Motif

Accessions: POU5F1_methyl_2 (HT-SELEX2 May2017)
Names: POU5F1
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Length: 15
Consensus: rTTAATTATGCGyrw
Weblogo:
PSSM: P0 A C G T
01 2817 1023 2025 609 r
02 383 1603 239 4872 T
03 377 100 37 6474 T
04 6474 54 76 205 A
05 6474 43 200 120 A
06 619 69 232 6474 T
07 20 5 6 6474 T
08 6474 0 8 8 A
09 154 36 159 6474 T
10 4 3 6474 758 G
11 2 6474 4 18 C
12 753 11 6474 288 G
13 1136 2569 769 2000 y
14 3748 530 2726 375 r
15 2232 987 1612 1645 w
Binding TFs: POU5F1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

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