DNA Binding Motif

Accessions: MA1112.2 (JASPAR 2024)
Names: NR4A1
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 12
Consensus: kwAAAGGTCAva
Weblogo:
PSSM: P0 A C G T
01 3484 3283 4159 5001 k
02 4463 3563 3380 4521 w
03 14313 236 823 555 A
04 15268 117 333 209 A
05 15684 62 128 53 A
06 427 92 12434 2974 G
07 300 166 14964 497 G
08 365 824 1358 13380 T
09 70 14949 151 757 C
10 15126 151 329 321 A
11 4456 3987 4075 3409 v
12 5239 3370 3887 3431 a
Type: Heterodimer
Binding TFs: P22736 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
P22736
Binding Sites: MA1112.2.1 / MA1112.2.2
MA1112.2.10 / MA1112.2.13
MA1112.2.11 / MA1112.2.14
MA1112.2.12 / MA1112.2.15
MA1112.2.13 / MA1112.2.16
MA1112.2.14 / MA1112.2.17
MA1112.2.15 / MA1112.2.18
MA1112.2.16 / MA1112.2.19
MA1112.2.17 / MA1112.2.20
MA1112.2.18
MA1112.2.19
MA1112.2.2 / MA1112.2.5
MA1112.2.20
MA1112.2.3 / MA1112.2.6
MA1112.2.4 / MA1112.2.7
MA1112.2.5 / MA1112.2.8
MA1112.2.6 / MA1112.2.9
MA1112.2.10 / MA1112.2.7
MA1112.2.11 / MA1112.2.8
MA1112.2.9
MA1112.2.1
MA1112.2.12
MA1112.2.3
MA1112.2.4
Publications: Wansa KD, Harris JM, Muscat GE. The activation function-1 domain of Nur77/NR4A1 mediates trans-activation, cell specificity, and coactivator recruitment. J Biol Chem 277:33001-11 (2002). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.