DNA Binding Motif

						

			
Accessions: 5u01_ABCD (3D-footprint 20231221)

			
Names: Transcription factor p65
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Cooperative DNA binding by two RelA dimers
Length: 23
Consensus: CGGAAnTTCCCGGGAAnTTCCGC
Weblogo: 
PSSM: P0      A      C      G      T
01      7     76      7      6      C
02      0      0     96      0      G
03      0      0     96      0      G
04     96      0      0      0      A
05     76      7      6      7      A
06     24     24     24     24      n
07      3      7     10     76      T
08      6      3      3     84      T
09      0     96      0      0      C
10      0     96      0      0      C
11      0     96      0      0      C
12      0      0     96      0      G
13      0      0     96      0      G
14      0      0     96      0      G
15     96      0      0      0      A
16     84      3      3      6      A
17     24     24     24     24      n
18      3      3      6     84      T
19      0      0      0     96      T
20      0     96      0      0      C
21      0     96      0      0      C
22      0      0     96      0      G
23      3     87      3      3      C
Binding TFs: 5u01_A / 5u01_B / 5u01_C / 5u01_D (Rel homology domain (RHD))
Binding Sites: 5u01_E / 5u01_F
			
Publications: Mulero MC, Huang DB, Nguyen HT, Wang V, Li Y, Biswas T, Ghosh G. DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor kappa B are not correlated. J Biol Chem : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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