DNA Binding Motif

Accessions: 5l0m_A (3D-footprint 20231221)
Names: Nuclear receptor subfamily 5 group A member 2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: hLRH-1 DNA Binding Domain - 12bp Oct4 promoter complex
Length: 9
Consensus: TAnCCTtGa
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 72 8 8 8 A
03 24 24 24 24 n
04 0 96 0 0 C
05 0 96 0 0 C
06 0 0 0 96 T
07 8 16 16 56 t
08 0 0 96 0 G
09 64 16 16 0 a
Binding TFs: 5l0m_A (Zinc finger, C4 type (two domains))
Binding Sites: 5l0m_B
5l0m_C
Publications: Weikum ER, Tuntland ML, Murphy MN, Ortlund EA. A Structural Investigation into Oct4 Regulation by Orphan Nuclear Receptors, Germ Cell Nuclear Factor (GCNF), and Liver Receptor Homolog-1 (LRH-1). J Mol Biol : (2016). [Pubmed]

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