DNA Binding Motif

Accessions: HOXD12_ETV1_1 (HumanTF2 1.0)
Names: HOXD12_ETV1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: rcCGGAAGTAATAAAm
Weblogo:
PSSM: P0 A C G T
01 1119 48 748 167 r
02 150 1388 478 58 c
03 19 1866 7 0 C
04 9 0 1866 0 G
05 0 0 1866 0 G
06 1866 0 0 16 A
07 1866 0 18 58 A
08 101 12 1866 0 G
09 5 293 13 1866 T
10 1866 459 95 31 A
11 1866 15 397 4 A
12 5 4 0 1866 T
13 1866 13 5 338 A
14 1866 0 0 9 A
15 1866 47 30 8 A
16 858 703 276 29 m
Type: Heterodimer
Binding TFs: ETV1_TF2 (Ets-domain)
HOXD12_TF1 (Homeobox domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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