DNA Binding Motif

Accessions: HOXB13_TBX21_2 (HumanTF2 1.0)
Names: HOXB13_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: ArGTGtkAmcwATAAA
Weblogo:
PSSM: P0 A C G T
01 684 0 135 115 A
02 226 4 458 7 r
03 52 54 684 17 G
04 71 0 111 684 T
05 48 0 684 17 G
06 138 98 41 407 t
07 70 93 342 179 k
08 497 0 172 25 A
09 237 212 90 145 m
10 79 397 51 157 c
11 314 117 4 250 w
12 684 0 0 18 A
13 5 0 13 684 T
14 684 17 39 19 A
15 684 21 56 0 A
16 684 13 0 51 A
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
TBX21_TF2 (T-box)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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