DNA Binding Motif

						

			
Accessions: HOXD12_TBX21_1 (HumanTF2 1.0)

			
Names: HOXD12_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: agGTGtkArGTCGTAAA
Weblogo: 
PSSM: P0      A      C      G      T
01    624     39    235    120      a
02    208    128    672    126      g
03      3     15    736     22      G
04      7    183      0    719      T
05     11      1    739      0      G
06     76    231     75    646      t
07     60    114    375    358      k
08    716      0     41     11      A
09    525     88    375    126      r
10     92    126    721      0      G
11     10     19      0    739      T
12     74    739     21     62      C
13    136      5    725      9      G
14      0      0      5    739      T
15    695      0      4    217      A
16    739      0      2     10      A
17    704     27     30     76      A
Type: Heterodimer
Binding TFs: HOXD12_TF1 (Homeobox domain)
TBX21_TF2 (T-box)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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