DNA Binding Motif

						

			
Accessions: TEAD4_FIGLA_2 (HumanTF2 1.0)

			
Names: TEAD4_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: GGwATGyvCAssTG
Weblogo: 
PSSM: P0      A      C      G      T
01   1782    264   7715    568      G
02    285    917   7715    361      G
03   7715   1293    122   6267      w
04   7715     23     39    137      A
05      8    514    141   7715      T
06     15    373   5986   1728      G
07    170   3022    361   4162      y
08   2440   2101   2622    552      v
09     11   7715     25     37      C
10   7715     92     73      0      A
11      0   2687   5027     35      s
12     64   3225   4490     37      s
13     36     41     57   7715      T
14     23      0   7715      0      G
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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