DNA Binding Motif

Accessions: PBX4_HOXA1 (HumanTF2 1.0)
Names: PBX4_HOXA1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 12
Consensus: vymATmAATCA-
Weblogo:
PSSM: P0 A C G T
01 1008 959 1252 430 v
02 441 1963 201 1685 y
03 929 1780 476 463 m
04 3648 199 336 87 A
05 14 242 57 3648 T
06 1502 2147 84 288 m
07 3648 859 381 167 A
08 3648 218 330 126 A
09 40 154 10 3648 T
10 104 3648 39 363 C
11 3648 600 376 671 A
12 0 0 0 0 -
Type: Heterodimer
Binding TFs: HOXA1_TF2 (Homeobox domain)
HOXA1_Full (Homeobox domain)
PBX4_TF1 (Homeobox domain, PBC domain, Homeobox KN domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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