DNA Binding Motif

Accessions: 6erq_BGJ (3D-footprint 20231221)
Names: Transcription factor A, mitochondrial
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of the human mitochondrial transcription initiation complex at the HSP promoter
Length: 34
Consensus: GCTGCTnnnnnnnTACCCnnnnnnnnnnnnATAG
Weblogo:
PSSM: P0 A C G T
01 6 6 78 6 G
02 0 96 0 0 C
03 0 0 0 96 T
04 0 0 96 0 G
05 0 96 0 0 C
06 6 6 6 78 T
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 24 24 24 24 n
12 24 24 24 24 n
13 24 24 24 24 n
14 0 0 0 96 T
15 96 0 0 0 A
16 0 96 0 0 C
17 0 96 0 0 C
18 6 78 6 6 C
19 24 24 24 24 n
20 24 24 24 24 n
21 24 24 24 24 n
22 24 24 24 24 n
23 24 24 24 24 n
24 24 24 24 24 n
25 24 24 24 24 n
26 24 24 24 24 n
27 24 24 24 24 n
28 24 24 24 24 n
29 24 24 24 24 n
30 24 24 24 24 n
31 96 0 0 0 A
32 6 6 6 78 T
33 96 0 0 0 A
34 6 6 78 6 G
Binding TFs: 6erq_G (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Binding Sites: 6erq_H
6erq_I
Publications: Hillen HS, Morozov YI, Sarfallah A, Temiakov D, Cramer P. Structural Basis of Mitochondrial Transcription Initiation. Cell 171:1072-1081 (2017). [Pubmed]

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