DNA Binding Motif

Accessions: 6m3d_C (3D-footprint 20231221)
Names: Segmentation polarity homeobox protein engrailed,Segmentation polarity homeobox protein engrailed
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: X-ray crystal structure of tandemly connected engrailed homeodomains (EHD) with R53A mutations and DNA complex
Length: 7
Consensus: CyAATCc
Weblogo:
PSSM: P0 A C G T
01 0 71 8 17 C
02 10 52 8 26 y
03 96 0 0 0 A
04 96 0 0 0 A
05 0 0 0 96 T
06 0 96 0 0 C
07 17 61 10 8 c
Binding TFs: 6m3d_C (Homeobox domain)
Binding Sites: 6m3d_A
6m3d_B
Publications: Sunami T, Hirano Y, Tamada T, Kono H. Structural basis for designing an array of engrailed homeodomains. Acta Crystallogr D Struct Biol : (2020). [Pubmed]

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