DNA Binding Motif

						

			
Accessions: ZNF12_2 (HT-SELEX2 May2017), UN0161.1 (JASPAR 2024)

			
Names: ZNF12
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 21
Consensus: GGksmTryTTGTTAymGCata
Weblogo: 
PSSM: P0      A      C      G      T
01    861    910   5135    317      G
02     28      0   5600     46      G
03    700     91   3642   1803      k
04    544   1625   3844    120      s
05   1806   3468    323    677      m
06      7     44     10   5610      T
07   2457    468   2821    379      r
08      6   3266    768   2190      y
09    138     78     43   5530      T
10      2   1394      0   5402      T
11     45     61   5610     20      G
12      1      0      0   5616      T
13      1    706      0   5562      T
14   4686      9    453    817      A
15    312   1899      5   3714      y
16   4540   2019     39    974      m
17     58     22   5385    705      G
18     93   5598     30     17      C
19   4834    397   1480    868      a
20    253   1342    922   3099      t
21   1993   1347   1219   1057      a
Type: Heterodimer
Binding TFs: ZNF12 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
P17014 (Zinc finger, C2H2 type, KRAB box, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
P17014
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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