DNA Binding Motif

Accessions: MA1941.2 (JASPAR 2024)
Names: ETV2::FIGLA
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 13
Consensus: sCGGAArCAGsTG
Weblogo:
PSSM: P0 A C G T
01 2429 8518 4342 832 s
02 2882 14178 1033 404 C
03 273 449 16064 222 G
04 308 212 16067 344 G
05 15973 604 522 593 A
06 14290 559 494 3629 A
07 9073 1959 4917 172 r
08 168 15983 414 688 C
09 16007 379 780 310 A
10 346 3705 15259 311 G
11 798 6725 12686 250 s
12 364 441 476 16024 T
13 385 241 16030 486 G
Type: Heterodimer
Binding TFs: Q6QHK4 (Helix-loop-helix DNA-binding domain)
Q6QHK4
Publications: Ibarra IL, Hollmann NM, Klaus B, Augsten S, Velten B, Hennig J, Zaugg JB. Mechanistic insights into transcription factor cooperativity and its impact on protein-phenotype interactions. Nat Commun 11:124 (2020). [Pubmed]

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