DNA Binding Motif

						

			
Accessions: FLI1_ONECUT2 (HumanTF2 1.0)

			
Names: FLI1_ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: acCGGAWryrmtgrTCGAT
Weblogo: 
PSSM: P0      A      C      G      T
01    164     47     69     53      a
02     31    174     60      1      c
03     47    233      5      0      C
04      0      0    233      8      G
05      0      2    233      5      G
06    233      1      0      7      A
07    233     14      0     86      W
08    103     11    120      0      r
09      9     67     47    111      y
10     81     53     60     39      r
11     77     65     55     36      m
12     27     57     50    100      t
13     39      2    139     52      g
14    144     13     89      7      r
15      0      0      0    233      T
16      5    233      5     35      C
17     30      5    233      3      G
18    233      8      0      9      A
19      0     15      8    233      T
Type: Heterodimer
Binding TFs: FLI1_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FLI1_Full (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
ONECUT2_TF2 (Homeobox domain, CUT domain)
ONECUT2_Full (Homeobox domain, CUT domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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