DNA Binding Motif

Accessions: ETV5_DRGX_2 (HumanTF2 1.0)
Names: ETV5_DRGX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: TaAtkrsCGGAwGy
Weblogo:
PSSM: P0 A C G T
01 57 0 50 245 T
02 245 12 54 65 a
03 245 26 14 48 A
04 35 15 89 245 t
05 29 35 99 146 k
06 169 23 76 15 r
07 10 161 83 0 s
08 49 245 22 2 C
09 0 6 245 0 G
10 0 0 245 17 G
11 245 10 0 0 A
12 171 4 9 73 w
13 2 18 245 15 G
14 31 97 16 100 y
Type: Heterodimer
Binding TFs: DRGX_TF2 (Homeobox domain)
ETV5_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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