DNA Binding Motif

						

			
Accessions: PBX4_HOXA10_2 (HumanTF2 1.0)

			
Names: PBX4_HOXA10
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 12
Consensus: vtcrTAAATCa-
Weblogo: 
PSSM: P0      A      C      G      T
01     86     64     87     18      v
02     64    109     20    255      t
03     49    255     10     98      c
04    245      1    255      0      r
05      4      0      1    255      T
06    255     20      8     38      A
07    255      8      3     44      A
08    255     12     20      0      A
09     20      0      0    255      T
10     17    255     17     13      C
11    255     57     30     72      a
12      0      0      0      0      -
Type: Heterodimer
Binding TFs: HOXA10_TF2 (Homeobox domain)
PBX4_TF1 (Homeobox domain, PBC domain, Homeobox KN domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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