DNA Binding Motif

Accessions: PBX4_HOXA10_2 (HumanTF2 1.0)
Names: PBX4_HOXA10
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 12
Consensus: vtcrTAAATCa-
Weblogo:
PSSM: P0 A C G T
01 86 64 87 18 v
02 64 109 20 255 t
03 49 255 10 98 c
04 245 1 255 0 r
05 4 0 1 255 T
06 255 20 8 38 A
07 255 8 3 44 A
08 255 12 20 0 A
09 20 0 0 255 T
10 17 255 17 13 C
11 255 57 30 72 a
12 0 0 0 0 -
Type: Heterodimer
Binding TFs: HOXA10_TF2 (Homeobox domain)
PBX4_TF1 (Homeobox domain, PBC domain, Homeobox KN domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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