DNA Binding Motif

						

			
Accessions: TEAD4_ELK1_1 (HumanTF2 1.0)

			
Names: TEAD4_ELK1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: ACCGGAhrTCCGGwATGh
Weblogo: 
PSSM: P0      A      C      G      T
01   1055     33    158     55      A
02    187   1212    150     73      C
03      7   1212      0      5      C
04      1      3   1212      1      G
05      0      0   1212      0      G
06   1212      2      2      0      A
07    416    368      0    430      h
08    448      8    764     83      r
09      0      8    123   1083      T
10      3   1076    134      0      C
11      8   1212     18     37      C
12      2      4   1212      0      G
13      0     15   1212    111      G
14    426     12     14    786      w
15   1212      3      0     49      A
16     14      0     27   1212      T
17      7     20    989    223      G
18    363    423     21    405      h
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
TEAD4_TF1 (TEA/ATTS domain family)
ELK1_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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