DNA Binding Motif

						

			
Accessions: 3nbn_AD (3D-footprint 20231221)

			
Names: Recombining binding protein suppressor of hairless
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of a dimer of Notch Transcription Complex trimers on HES1 DNA
Length: 30
Consensus: CTgTGGGAAnnnnnnnnnnnnnnnTTCnCA
Weblogo: 
PSSM: P0      A      C      G      T
01      6     81      6      3      C
02      0      3      4     89      T
03     10     10     65     11      g
04      0      0      0     96      T
05      0      0     96      0      G
06      6      6     78      6      G
07      0      0     96      0      G
08     96      0      0      0      A
09     87      6      3      0      A
10     24     24     24     24      n
11     24     24     24     24      n
12     24     24     24     24      n
13     24     24     24     24      n
14     24     24     24     24      n
15     24     24     24     24      n
16     24     24     24     24      n
17     24     24     24     24      n
18     24     24     24     24      n
19     24     24     24     24      n
20     24     24     24     24      n
21     24     24     24     24      n
22     24     24     24     24      n
23     24     24     24     24      n
24     24     24     24     24      n
25     10      3      8     75      T
26      0      0      0     96      T
27      0     96      0      0      C
28     24     24     24     24      n
29      3     92      1      0      C
30     85      3      5      3      A
Binding TFs: 3nbn_A / 3nbn_D (IPT/TIG domain, Beta-trefoil DNA-binding domain, LAG1, DNA binding)
Binding Sites: 3nbn_X
3nbn_Y
			
Publications: Arnett K.L, Hass M, McArthur D.G, Ilagan M.X, Aster J.C, Kopan R, Blacklow S.C. Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes. Nature structural & molecular biology 17:1312-7 (2010). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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