DNA Binding Motif

Accessions: GCM1_TBX21_2 (HumanTF2 1.0)
Names: GCM1_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 28
Consensus: rgGTGtkAhyyhmhtkTmrCATrcGGGy
Weblogo:
PSSM: P0 A C G T
01 2260 365 1290 1181 r
02 932 657 2436 736 g
03 199 90 2703 335 G
04 38 1342 202 4535 T
05 130 46 2778 48 G
06 516 1215 334 3843 t
07 479 1141 1619 1545 k
08 2968 235 726 248 A
09 1281 1280 659 1112 h
10 931 1019 920 1191 y
11 880 1174 594 1775 y
12 1079 1236 772 1167 h
13 1135 1246 799 1033 m
14 1208 1113 828 1095 h
15 1046 841 837 1525 t
16 773 659 1072 1614 k
17 435 996 166 4436 T
18 1628 1607 619 661 m
19 1605 456 1161 687 r
20 259 5668 147 206 C
21 3462 69 722 20 A
22 214 521 78 4679 T
23 2290 127 1346 42 r
24 331 2998 521 933 c
25 665 107 2658 203 G
26 47 138 2678 148 G
27 11 155 2692 117 G
28 697 2209 251 1608 y
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
TBX21_TF2 (T-box)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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