DNA Binding Motif

						

			
Accessions: 2o61_AB (3D-footprint 20231221)

			
Names: Transcription factor p65/Interferon regulatory factor 7/Interferon regulatory factor 3 fusion protein
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of NFkB, IRF7, IRF3 bound to the interferon-b enhancer
Length: 26
Consensus: GGAGAnnTTAAnnTGGGAAnTTCCTC
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02     12      9     66      9      G
03     93      1      1      1      A
04      0      0     96      0      G
05     72      5      5     14      A
06     24     24     24     24      n
07     24     24     24     24      n
08      1      1      4     90      T
09      3      5     14     74      T
10     84      1      5      6      A
11     96      0      0      0      A
12     24     24     24     24      n
13     24     24     24     24      n
14      5      3      3     85      T
15      0      0     96      0      G
16      0      0     96      0      G
17      0      0     96      0      G
18     96      0      0      0      A
19     82      3      4      7      A
20     24     24     24     24      n
21      1      4      5     86      T
22      0      0      0     96      T
23      0     96      0      0      C
24      0     96      0      0      C
25      0      0      0     96      T
26      5     82      6      3      C
Type: Heterodimer
Binding TFs: 2o61_A (Rel homology domain (RHD), Interferon regulatory factor transcription factor)
2o61_B (Rel homology domain (RHD))
Binding Sites: 2o61_E
2o61_F
			
Publications: Panne D, Maniatis T, Harrison S.C. An atomic model of the interferon-beta enhanceosome. Cell 129:1111-23 (2007). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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