DNA Binding Motif

						

			
Accessions: GCM2_SOX15_2 (HumanTF2 1.0)

			
Names: GCM2_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: aTrcGGGydwwttyyaTTGTyt
Weblogo: 
PSSM: P0      A      C      G      T
01    206     37     51     18      a
02     23     13     43    257      T
03     77     12    180      2      r
04     72    257    118     46      c
05     39     10    257     30      G
06      8      3    257      0      G
07      0      3    257      0      G
08     13     79     25    141      y
09     89     36     66     66      d
10     72     48     43     94      w
11     79     51     56     71      w
12     58     36     60    103      t
13     18     58     63    118      t
14      9     89     58    101      y
15     53    122     35    135      y
16    177     27     41     80      a
17     35     25     24    257      T
18     32     29      9    257      T
19     44     33    257     44      G
20     38     23     12    257      T
21     21     72     48    116      y
22     56     39     17    144      t
Type: Heterodimer
Binding TFs: GCM2_TF1 (GCM motif protein)
SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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