DNA Binding Motif

						

			
Accessions: TFAP2C_MAX_2_3_4 (HumanTF2 1.0)

			
Names: TFAP2C_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 31
Consensus: tgsCCysrGGssayrysssvssrrsCACGTG
Weblogo: 
PSSM: P0      A      C      G      T
01   6491   6257   4061  12025      t
02   2653   2747   4310   2315      g
03    328   4679   7346    522      s
04     65  12025    628     61      C
05     19  12025    438   1854      C
06    406   4240   2186   5192      y
07   1970   4269   3754   2032      s
08   5407   2600   3702    316      r
09   2407    336  12025    102      G
10     85    316  12025     48      G
11    481   7365   4660    453      s
12   2436   3380   3880   2328      s
13   5584   2146   2337   1957      a
14   2667   3419   1976   3962      y
15   3472   2319   3640   2593      r
16   2746   3441   2740   3098      y
17   2431   3386   3721   2487      s
18   2385   3483   4280   1878      s
19   2639   3165   3940   2281      s
20   3114   3438   3193   2279      v
21   2446   3712   3299   2569      s
22   2652   3324   3325   2725      s
23   3346   2370   3313   2995      r
24   4014   2003   4329   1678      r
25   2621   3457   3951   1996      s
26     94  12025     52      0      C
27  12025     89     85     97      A
28      0  12025     77    164      C
29    260     36  12025     69      G
30      6    135    150  12025      T
31    214      0  12025     80      G
Type: Heterodimer
Binding TFs: MAX_TF2 (Helix-loop-helix DNA-binding domain)
TFAP2C_TF1 (Transcription factor AP-2)
MAX_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.