DNA Binding Motif

Accessions: FOXO1_HOXA10 (HumanTF2 1.0)
Names: FOXO1_HOXA10
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: rwmAACAycrTwAa
Weblogo:
PSSM: P0 A C G T
01 46 22 58 4 r
02 42 15 14 63 w
03 57 47 2 22 m
04 105 18 3 8 A
05 105 6 7 7 A
06 2 105 7 10 C
07 105 13 19 3 A
08 31 39 9 66 y
09 29 105 16 11 c
10 52 6 53 12 r
11 16 15 7 105 T
12 59 16 4 46 w
13 105 9 8 14 A
14 105 28 14 34 a
Type: Heterodimer
Binding TFs: FOXO1_TF1 / FOXO1_TF2 (Fork head domain)
HOXA10_TF2 (Homeobox domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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