DNA Binding Motif

Accessions: 6omf_F (3D-footprint 20231221)
Names: RNA polymerase sigma factor RpoS
Organisms: Salmonella enterica subsp. enterica serovar Typhimurium
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CryoEM structure of SigmaS-transcription initiation complex with activator Crl
Length: 29
Consensus: TAACgnGAGCAnCnnnnnnnnnnnncGcT
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 96 0 0 0 A
03 96 0 0 0 A
04 0 96 0 0 C
05 11 11 62 12 g
06 24 24 24 24 n
07 0 0 96 0 G
08 96 0 0 0 A
09 0 0 96 0 G
10 0 96 0 0 C
11 96 0 0 0 A
12 24 24 24 24 n
13 7 79 5 5 C
14 24 24 24 24 n
15 24 24 24 24 n
16 24 24 24 24 n
17 24 24 24 24 n
18 24 24 24 24 n
19 24 24 24 24 n
20 24 24 24 24 n
21 24 24 24 24 n
22 24 24 24 24 n
23 24 24 24 24 n
24 24 24 24 24 n
25 24 24 24 24 n
26 18 56 11 11 c
27 0 0 96 0 G
28 11 62 11 12 c
29 0 0 0 96 T
Binding TFs: 6omf_F (Sigma-70 factor, region 1.2, Sigma-70 region 3, Sigma-70 region 2 , Sigma-70, region 4)
Binding Sites: 6omf_N
6omf_T
Publications: Cartagena AJ, Banta AB, Sathyan N, Ross W, Gourse RL, Campbell EA, Darst SA. Structural basis for transcription activation by Crl through tethering of σ(S) and RNA polymerase. Proc Natl Acad Sci U S A 116:18923-18927 (2019). [Pubmed]

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