DNA Binding Motif

Accessions: UP00383A_1 (UniPROBE 20160601)
Names: hlh-24, REF-1
Organisms: Caenorhabditis elegans
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 17
Consensus: wmawgGCACGTGycwwa
Weblogo:
PSSM: P0 A C G T
01 0.35 0.14 0.15 0.37 w
02 0.27 0.31 0.22 0.20 m
03 0.51 0.18 0.11 0.20 a
04 0.34 0.22 0.16 0.28 w
05 0.23 0.03 0.68 0.07 g
06 0.22 0.08 0.69 0.02 G
07 0.01 0.98 0.01 0.01 C
08 0.96 0.01 0.03 0.01 A
09 0.01 0.97 0.01 0.02 C
10 0.01 0.01 0.97 0.01 G
11 0.01 0.02 0.01 0.96 T
12 0.01 0.01 0.98 0.01 G
13 0.01 0.45 0.09 0.45 y
14 0.21 0.47 0.10 0.21 c
15 0.30 0.19 0.17 0.34 w
16 0.34 0.07 0.20 0.38 w
17 0.50 0.13 0.15 0.22 a
Binding TFs: UP00383A (Helix-loop-helix DNA-binding domain)
Binding Sites: AAAAAATA
AAATAAAA
AACACGTG
ACACGTGC
ACACGTGG
ACACGTGT
ACCACGTG
AGCACGTG
CACACGTG
CACGTGCA
CACGTGCC
CACGTGCG
CACGTGGA
CACGTGGC
CACGTGTA
CACGTGTC
CCACGTGC
CCACGTGG
GCACGTGC
ATAAAAAT
Publications: Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed]

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