DNA Binding Motif

						

			
Accessions: 6p0t_ABE (3D-footprint 20231221)

			
Names: DNA-binding protein Fis
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of ternary DNA complex "FX(1-2)-1Xis" containing E. coli Fis and phage lambda Xis
Length: 20
Consensus: TGTnTTnnnnACAGACTAnA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02      3      3     87      3      G
03      0      0      0     96      T
04     24     24     24     24      n
05      3      3      3     87      T
06      0      0      0     96      T
07     24     24     24     24      n
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11     84      3      6      3      A
12      0     96      0      0      C
13     84      3      3      6      A
14      6      3     84      3      G
15     96      0      0      0      A
16      0     96      0      0      C
17      3      6      3     84      T
18     81      3      7      5      A
19     24     24     24     24      n
20     84      3      3      6      A
Type: Heterodimer
Binding TFs: 6p0t_B (Bacterial regulatory protein, Fis family)
6p0t_A (Bacterial regulatory protein, Fis family)
Binding Sites: 6p0t_C
6p0t_D
			
Publications: Hancock SP, Cascio D, Johnson RC. Cooperative DNA binding by proteins through DNA shape complementarity. Nucleic Acids Res 47:8874-8887 (2019). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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