DNA Binding Motif

						

			
Accessions: CLOCK_EVX1_2 (HumanTF2 1.0)

			
Names: CLOCK_EVX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: CACGTGysGTAATgAT
Weblogo: 
PSSM: P0      A      C      G      T
01      1   1859      0      0      C
02   1859     27     70      0      A
03      5   1859      0    117      C
04     13      0   1859      4      G
05     24     55     22   1859      T
06      4      3   1859     15      G
07     22    542    100   1195      y
08    350    507    971     30      s
09     74    274   1331    179      G
10    190    320     29   1859      T
11   1859    341     88     37      A
12   1859     46     12      0      A
13      9    197     27   1859      T
14    280    458   1431    427      g
15   1859     14      1      0      A
16     59     39     98   1859      T
Type: Heterodimer
Binding TFs: CLOCK_TF1 / CLOCK_TF2 (Helix-loop-helix DNA-binding domain)
EVX1_TF1 / EVX1_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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