DNA Binding Motif

						

			
Accessions: ERF_ONECUT2 (HumanTF2 1.0)

			
Names: ERF_ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: rCCGGAArtgcsgATCGATy
Weblogo: 
PSSM: P0      A      C      G      T
01    247     51    205     99      r
02     79    404     48     15      C
03    120    451      8      0      C
04      0      0    451      3      G
05      0      2    451      0      G
06    451      0     25      0      A
07    451      1      5     19      A
08    147     75    221      8      r
09     79     89     31    252      t
10     97     55    193    105      g
11     91    173    110     77      c
12     83    163    137     69      s
13     82     55    226     88      g
14    350     19    101      0      A
15     35     18      2    451      T
16     12    451      4     48      C
17     94     15    451      5      G
18    451      1     11     37      A
19     31     15      0    451      T
20     88    122     91    150      y
Type: Heterodimer
Binding TFs: ONECUT2_TF2 (Homeobox domain, CUT domain)
ERF_TF1 (Ets-domain)
ONECUT2_Full (Homeobox domain, CUT domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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