DNA Binding Motif

						

			
Accessions: POU2F1_ETV4_1 (HumanTF2 1.0), POU2F1_ETV4_2 (HumanTF2 1.0)

			
Names: POU2F1_ETV4
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: ACCGgATATGCAd
Weblogo: 
PSSM: P0      A      C      G      T
01   1264      5     14     42      A
02     25   1326    241     27      C
03     50   1326      8      3      C
04     11     23   1326      0      G
05    403    230   1326      5      g
06   1326     75     48     91      A
07    355      0     14   1326      T
08   1326      0      2      0      A
09      0      3      4   1326      T
10      0      0   1326     10      G
11      7   1326      0     83      C
12   1326     26    228     17      A
13    448    150    363    365      d
Type: Heterodimer
Binding TFs: ETV4_TF2 (Ets-domain)
POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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