DNA Binding Motif

						

			
Accessions: POU2F1_HOXB13 (HumanTF2 1.0)

			
Names: POU2F1_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: wrmATAwwCmAATAAA
Weblogo: 
PSSM: P0      A      C      G      T
01    811    525    335   1393      w
02    886    250   2126     99      r
03   1637   1325    155    255      m
04   2911     51    264    343      A
05     43    256     52   2996      T
06   3060     27     60     37      A
07   1384     34    137   2775      w
08   2806     38    573   1379      w
09    118   3058     37     63      C
10   1239   2707    119    362      m
11   2907    455    174    512      A
12   2830     22    619    160      A
13     51     40      0   3054      T
14   2748     27    307    733      A
15   3017     10     34    186      A
16   2720    378    230    284      A
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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