DNA Binding Motif

						

			
Accessions: TEAD4_CLOCK_1 (HumanTF2 1.0)

			
Names: TEAD4_CLOCK
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: rCAcRTGybmcarcATwCy
Weblogo: 
PSSM: P0      A      C      G      T
01    109     23     59      7      r
02     18    198      8     18      C
03    198      3      5      0      A
04     28    198     28     48      c
05     75      7    198      6      R
06      1     32     24    198      T
07     28      7    198     56      G
08     21     67     21     90      y
09     46     50     51     52      b
10     64     80      9     46      m
11     35     79     42     42      c
12     90     43     27     39      a
13    101     33     65      0      r
14     72    198     17     21      c
15    198      0      6      0      A
16      0     12      0    198      T
17     84      1     31    114      w
18     42    198     26      0      C
19     22    198      0    105      y
Type: Heterodimer
Binding TFs: CLOCK_TF1 / CLOCK_TF2 (Helix-loop-helix DNA-binding domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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