DNA Binding Motif

						

			
Accessions: GCM2_FIGLA_2 (HumanTF2 1.0)

			
Names: GCM2_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: mCAssTGkdwyswbkATGCGGG
Weblogo: 
PSSM: P0      A      C      G      T
01    448    574    298    322      m
02     17   1642     54      0      C
03   1642      0    162     69      A
04     37    516   1126     13      s
05     10    741    901     41      s
06      0      5    104   1642      T
07     26      2   1642     53      G
08    118    285    566    674      k
09    414    184    412    632      d
10    465    407    286    485      w
11    295    462    364    521      y
12    330    496    414    402      s
13    456    209    365    612      w
14    326    429    430    457      b
15    222    359    589    472      k
16   1340    146    302     99      A
17     27      9     26   1642      T
18    423     76   1219      7      G
19    215   1642    251    294      C
20    131     10   1642     57      G
21      0      0   1642      0      G
22      0     12   1642     44      G
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
GCM2_TF1 (GCM motif protein)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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