DNA Binding Motif

						

			
Accessions: TEAD4_SPIB_1 (HumanTF2 1.0), UN0586.1 (JASPAR 2024)

			
Names: TEAD4_SPIB, TEAD4::SPIB
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 14
Consensus: rGAATGCGGAAGTd
Weblogo: 
PSSM: P0      A      C      G      T
01    729     96   1028    225      r
02    533     51   1757     90      G
03   1757     13      5     36      A
04   1757      2      2    119      A
05    191      3      9   1757      T
06     21     55   1757      1      G
07    458   1757    211      1      C
08     11      0   1757      0      G
09      1      1   1757      2      G
10   1757      1      0      1      A
11   1757      1      2     11      A
12     26    365   1757      0      G
13     58    146     47   1757      T
14    593    258    442    464      d
Type: Heterodimer
Binding TFs: SPIB_TF1 / SPIB_TF2 (Ets-domain)
TEAD4_TF1 (TEA/ATTS domain family)
Q15561 (TEA/ATTS domain family)
Q15561
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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