DNA Binding Motif

						

			
Accessions: UP00599C_1 (UniPROBE 20160601)

			
Names: EKLF, Erythroid krueppel-like transcription factor, HBFQTL6, INLU, KLF1_H299Y_R1, Krueppel-like factor 1
Organisms: Homo sapiens
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 23
Consensus: wttwwcCmCGCCCmcCCattcys
Weblogo: 
PSSM: P0      A      C      G      T
01   0.36   0.07   0.07   0.50      w
02   0.15   0.24   0.06   0.55      t
03   0.23   0.24   0.14   0.39      t
04   0.39   0.17   0.13   0.32      w
05   0.27   0.12   0.18   0.43      w
06   0.17   0.63   0.04   0.16      c
07   0.05   0.71   0.02   0.22      C
08   0.29   0.67   0.02   0.02      m
09   0.03   0.95   0.01   0.01      C
10   0.09   0.01   0.83   0.08      G
11   0.01   0.96   0.01   0.02      C
12   0.02   0.95   0.01   0.02      C
13   0.01   0.95   0.01   0.03      C
14   0.42   0.32   0.03   0.23      m
15   0.24   0.34   0.18   0.23      c
16   0.06   0.78   0.04   0.11      C
17   0.08   0.73   0.05   0.14      C
18   0.62   0.09   0.12   0.16      a
19   0.23   0.13   0.18   0.46      t
20   0.19   0.09   0.12   0.59      t
21   0.24   0.54   0.08   0.14      c
22   0.19   0.37   0.08   0.36      y
23   0.16   0.37   0.28   0.19      s
Binding TFs: UP00599C (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: CCCGCCCC
ACGCCCAT
ACGCCCCC
AGGGCGGG
AGGGGCGG
CCCCGCCC
CCCGCCCA
CCGCCCCA
GGGGCGTA
ACGCCCAA
AGGGCGTA
ATACGCCC
ATCCGCCC
ATGGGCGG
GGGCGGGA
GGGCGGTA
GGGCGTAA
GGGGCGGA
TACGCCCA
TCCGCCCA
			
Publications: Barrera LA, Vedenko A, Kurland JV, Rogers JM, Gisselbrecht SS, Rossin EJ, Woodard J, Mariani L, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, Hao T, Yi S, Kellis M, Daly MJ, Vidal M, Hill DE, Bulyk ML. Survey of variation in human transcription factors reveals prevalent DNA binding changes. Science 351:1450-4 (2016). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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