DNA Binding Motif

						

			
Accessions: ERF_SREBF2_1 (HumanTF2 1.0)

			
Names: ERF_SREBF2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: rTCACGTGACmGGAAgkr
Weblogo: 
PSSM: P0      A      C      G      T
01     93      9     37      0      r
02      1      3      3    131      T
03      3    138      0      2      C
04    138      7     12      1      A
05      0    138     17      2      C
06      0     10    138      0      G
07      0      1      0    138      T
08      3      6    138      0      G
09    138     10      3      5      A
10      1    138      5     12      C
11     45     93      1      2      m
12      0      1    138      2      G
13      2     10    138      6      G
14    138      0      3     11      A
15    138      9      1     20      A
16     32     13    106      9      g
17      2      7     55     74      k
18     42     34     56      7      r
Type: Heterodimer
Binding TFs: SREBF2_TF2 (Helix-loop-helix DNA-binding domain)
ERF_TF1 (Ets-domain)
SREBF2_TF1 (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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