DNA Binding Motif

						

			
Accessions: POU2F1_EOMES_2_3_4 (HumanTF2 1.0)

			
Names: POU2F1_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: gawTATkCAGyGtkA
Weblogo: 
PSSM: P0      A      C      G      T
01   1099   1115   1605   1083      g
02   2224   1090    627    961      a
03   1945    540   1047   1370      w
04    375   1050    315   4902      T
05   4902      0      1     33      A
06    224    163    112   4902      T
07    567     33   4902   3048      k
08     59   4902    293    385      C
09   4902     89   1065    627      A
10    169   1000   4902    415      G
11    295   2341    102   2561      y
12    157      9   4902     23      G
13   1147   1877    358   4902      t
14    743   1043   2727   2175      k
15   4902    359    979    400      A
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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