DNA Binding Motif

Accessions: 5d8k_B (3D-footprint 20231221)
Names: Heat shock factor protein 2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Human HSF2 DNA-Binding Domain bound to 2-site HSE DNA at 1.73 Angstroms Resolution
Length: 4
Consensus: gTTc
01 13 13 57 13 g
02 0 0 0 96 T
03 0 0 0 96 T
04 13 54 13 16 c
Binding TFs: 5d8k_B (HSF-type DNA-binding)
Binding Sites: 5d8k_A
Publications: Jaeger AM, Pemble CW 4th, Sistonen L, Thiele DJ. Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors. Nat Struct Mol Biol 23:147-54 (2016). [Pubmed]

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