DNA Binding Motif

						

			
Accessions: ETV2_SREBF2_1 (HumanTF2 1.0)

			
Names: ETV2_SREBF2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: rTCACGysACCGGAwr
Weblogo: 
PSSM: P0      A      C      G      T
01    260     88    151      6      r
02     31     22     17    411      T
03     16    411     59      7      C
04    411     11     92     32      A
05     28    411     59     16      C
06     47    105    411     10      G
07      7    223      3    188      y
08      1    222    189     19      s
09    375      4     14     19      A
10     25    411     56     24      C
11     73    411     54     10      C
12     11      2    411     20      G
13      0     68    411      5      G
14    411     28     34      7      A
15    238     62     20    173      w
16    106     99    150     56      r
Type: Heterodimer
Binding TFs: SREBF2_TF2 (Helix-loop-helix DNA-binding domain)
ETV2_TF1 (Ets-domain)
SREBF2_TF1 (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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