DNA Binding Motif

Accessions: ETV2_TCF3 (HumanTF2 1.0)
Names: ETV2_TCF3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: CAssTGmacCGGAwrys
Weblogo:
PSSM: P0 A C G T
01 43 728 32 94 C
02 728 53 81 38 A
03 12 392 336 36 s
04 23 353 376 18 s
05 36 88 52 728 T
06 36 31 728 68 G
07 237 198 138 155 m
08 475 67 97 90 a
09 293 728 258 126 c
10 109 728 24 4 C
11 1 3 728 4 G
12 1 0 728 0 G
13 728 5 1 9 A
14 444 59 9 284 w
15 261 71 468 19 r
16 76 322 124 407 y
17 151 185 246 146 s
Type: Heterodimer
Binding TFs: TCF3_TF2 (Helix-loop-helix DNA-binding domain)
ETV2_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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