DNA Binding Motif

						

			
Accessions: POU2F1_DLX2_2_3 (HumanTF2 1.0), UN0577.1 (JASPAR 2024)

			
Names: POU2F1_DLX2, POU2F1::DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 17
Consensus: wTwTGCRwAkyYAATtr
Weblogo: 
PSSM: P0      A      C      G      T
01    655     14     15    373      w
02    147     54      0   1028      T
03    325     47      0    703      w
04     38     83      0   1028      T
05      9      3   1028     59      G
06     44   1028     56      4      C
07   1028      8    459      2      R
08    454    107     30   1028      w
09   1028     57     69    197      A
10     48     38    372    570      k
11     96    418    130    384      y
12     23    354      8   1028      Y
13   1028     23     26      0      A
14   1028      6      0     16      A
15     58      0     38   1028      T
16    292     51    383   1028      t
17   1028      7   1034     49      r
Type: Heterodimer
Binding TFs: Q07687 (Homeobox domain, Homeobox protein distal-less-like N terminal )
DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
Q07687
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.