DNA Binding Motif

						

			
Accessions: UP00502A_1 (UniPROBE 20160601)

			
Names: S. purpuratus Tbrain (T-box transcription factor), SpTbr_rep1
Organisms: Strongylocentrotus purpuratus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 23
Consensus: ycgswvdAGGTGTGAAydrkwch
Weblogo: 
PSSM: P0      A      C      G      T
01   0.05   0.45   0.13   0.37      y
02   0.20   0.49   0.22   0.09      c
03   0.14   0.10   0.56   0.20      g
04   0.16   0.28   0.37   0.19      s
05   0.41   0.22   0.11   0.26      w
06   0.32   0.26   0.31   0.12      v
07   0.31   0.08   0.33   0.29      d
08   0.94      0   0.06   0.01      A
09   0.02   0.01   0.96   0.01      G
10      0      0   0.98   0.01      G
11      0   0.05      0   0.94      T
12   0.01      0   0.98      0      G
13   0.01   0.09      0   0.90      T
14   0.01   0.11   0.81   0.08      G
15   0.95      0   0.05      0      A
16   0.85   0.03   0.08   0.04      A
17   0.10   0.55   0.04   0.32      y
18   0.26   0.16   0.31   0.27      d
19   0.29   0.19   0.32   0.20      r
20   0.13   0.16   0.41   0.31      k
21   0.36   0.09   0.12   0.43      w
22   0.24   0.31   0.22   0.23      c
23   0.35   0.25   0.03   0.37      h
Binding TFs: UP00502A (T-box)
Binding Sites: AAGTGTGA
AGGTGAGA
AGGTGCGA
AGGTGTCA
AGGTGTGA
AGGTGTTA
AGTGTGAA
ATCACACC
ATGTGTGA
CTTCACAC
GGGTGTGA
GGTGTGAA
GTGTGAAA
GTGTGAAC
AAGTGCGA
AGGTGCTA
CACACCTC
CTCACACC
GATCACAC
TGTGTGAA
			
Publications: Cheatle Jarvela AM, Brubaker L, Vedenko A, Gupta A, Armitage BA, Bulyk ML, Hinman VF. Modular evolution of DNA-binding preference of a Tbrain transcription factor provides a mechanism for modifying gene regulatory networks. Mol Biol Evol 31:2672-88 (2014). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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