DNA Binding Motif

						

			
Accessions: CLOCK_NHLH1_2 (HumanTF2 1.0)

			
Names: CLOCK_NHLH1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: mgCAgcTGyscmvCACGTGbm
Weblogo: 
PSSM: P0      A      C      G      T
01    226    336     50    183      m
02    221     23    573    156      g
03     61    795      0     12      C
04    795     19     11     15      A
05     41    245    795    153      g
06    158    795    288    107      c
07     72     14      7    795      T
08     42     24    795      4      G
09    182    335     36    242      y
10     76    242    308    169      s
11    140    366    139    149      c
12    256    291    145    103      m
13    291    261    244      0      v
14     16    795      0      0      C
15    795      0     28      2      A
16      1    795      0     38      C
17     20     12    795      6      G
18     12     15      7    795      T
19      0      0    795    138      G
20      3    293    205    294      b
21    271    306    115    104      m
Type: Heterodimer
Binding TFs: CLOCK_TF1 / CLOCK_TF2 (Helix-loop-helix DNA-binding domain)
NHLH1_TF2 (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.