DNA Binding Motif

						

			
Accessions: TEAD4_SPDEF_2_3 (HumanTF2 1.0)

			
Names: TEAD4_SPDEF
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: rGwATGCGGAwrTrbaTCCGkby
Weblogo: 
PSSM: P0      A      C      G      T
01    927      6   1330    251      r
02     21    269   2250    128      G
03   1598    107      8    681      w
04   2270      0      0     28      A
05      4     44    109   2208      T
06      2     14   2264      9      G
07    169   2150      0      0      C
08     12      8   2280      4      G
09      0      4   2283      8      G
10   2246      6     52    454      A
11    838    379    242   1769      w
12    780    200   1915    137      r
13    113    229    143   1798      T
14    766     36   1262    218      r
15    182    657    629    815      b
16   1158    218    347    559      a
17     95      9     74   2220      T
18      1   2267     36     29      C
19      4   2287     60    201      C
20      5    157   1638    556      G
21    105    215   1300    662      k
22    184    714    628    757      b
23    514    576    340    853      y
Type: Heterodimer
Binding TFs: SPDEF_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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