DNA Binding Motif

						

			
Accessions: HOXB2_SOX15_1 (HumanTF2 1.0)

			
Names: HOXB2_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: ACAATrsmawssymaTya
Weblogo: 
PSSM: P0      A      C      G      T
01    201      0     13     20      A
02      0    201     13     65      C
03    201      3     11      2      A
04    201      2      0     25      A
05     50      0      3    150      T
06     67     22    133     38      r
07     58     68    133      8      s
08     64     76     38     22      m
09     86     40     44     29      a
10     80     38     28     55      w
11     48     63     58     32      s
12     45     56     68     31      s
13     37    122     31     79      y
14    115     86     57     25      m
15    201     42     26     27      a
16     13      4     11    201      T
17     27    101     38    201      y
18    201     13     57     28      a
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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