DNA Binding Motif

Accessions: RFX3_ETV7 (HumanTF2 1.0)
Names: RFX3_ETV7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 25
Consensus: ascmGGAAgyryTTCCyTrgCaACs
Weblogo:
PSSM: P0 A C G T
01 211 48 115 119 a
02 98 178 147 71 s
03 93 284 66 51 c
04 204 290 56 24 m
05 13 3 494 0 G
06 0 4 494 0 G
07 494 4 0 12 A
08 494 47 2 72 A
09 116 77 281 20 g
10 74 142 45 233 y
11 216 56 140 82 r
12 13 310 46 125 y
13 64 0 24 409 T
14 4 2 0 494 T
15 5 494 2 4 C
16 2 494 0 0 C
17 11 182 82 219 y
18 18 49 76 352 T
19 236 59 182 17 r
20 146 53 348 47 g
21 26 494 24 62 C
22 494 15 170 134 a
23 494 26 42 25 A
24 6 494 0 26 C
25 72 147 238 36 s
Type: Heterodimer
Binding TFs: ETV7_TF1 / ETV7_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
RFX3_TF1 (RFX DNA-binding domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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