DNA Binding Motif

						

			
Accessions: UP00148A_1 (UniPROBE 20160601)

			
Names: Hdx, Highly divergent homeobox, Not Available
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 17
Consensus: wrkkmGAAATCAtcbha
Weblogo: 
PSSM: P0      A      C      G      T
01   0.31   0.20   0.21   0.27      w
02   0.34   0.18   0.26   0.22      r
03   0.05   0.09   0.52   0.35      k
04   0.20   0.12   0.35   0.33      k
05   0.30   0.31   0.16   0.24      m
06   0.21   0.02   0.72   0.04      G
07   0.70   0.23   0.05   0.02      A
08   0.83   0.01   0.06   0.10      A
09   0.92   0.01   0.03   0.05      A
10   0.02   0.02   0.03   0.93      T
11   0.03   0.90   0.04   0.03      C
12   0.86   0.04   0.01   0.08      A
13   0.18   0.22   0.16   0.45      t
14   0.23   0.33   0.20   0.24      c
15   0.14   0.30   0.31   0.26      b
16   0.34   0.35   0.06   0.26      h
17   0.40   0.23   0.19   0.18      a
Binding TFs: UP00148A (Homeobox domain)
Binding Sites: AAAAATCA
AAATCATG
AACAATCA
ACAATCAC
ACAATCAG
ACAATCAT
ACGATCAT
ACTATCAT
AGAAATCA
ATGATTGC
ATGATTTC
CACAATCA
CGAAATCA
GCAATCAC
TAAGATCA
TACAATCA
TACGATCA
TGAAATCA
TGATATCA
TGATTGCA
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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