DNA Binding Motif
| Accessions: | UP00521A_2 (UniPROBE 20160601), UP00530A_2 (UniPROBE 20160601) |
| Names: | FOXN2, HTLF, Human T-cell leukemia virus enhancer factor, FoxN2-3_Nvec, N.vec FoxN2/3 |
| Organisms: | Homo sapiens, Nematostella vectensis |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Length: | 22 |
| Consensus: | mrtrygAyCGCGTCmTdawwrr |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0.34 0.30 0.18 0.18 m 02 0.25 0.22 0.29 0.24 r 03 0.17 0.04 0.21 0.58 t 04 0.34 0.01 0.41 0.23 r 05 0.20 0.32 0.20 0.28 y 06 0.14 0.19 0.46 0.21 g 07 0.81 0.03 0.09 0.07 A 08 0.14 0.36 0.07 0.44 y 09 0.16 0.68 0.15 0.01 C 10 0 0 0.99 0 G 11 0.01 0.98 0 0.01 C 12 0.01 0 0.98 0.01 G 13 0.01 0 0.01 0.98 T 14 0 0.97 0.01 0.02 C 15 0.34 0.30 0.21 0.15 m 16 0.07 0.12 0.02 0.80 T 17 0.25 0.19 0.27 0.28 d 18 0.57 0.10 0.17 0.16 a 19 0.50 0.07 0.07 0.35 w 20 0.47 0.06 0.13 0.33 w 21 0.41 0.11 0.30 0.18 r 22 0.27 0.12 0.38 0.23 r |
| Type: | Heterodimer |
| Binding TFs: | UP00521A (Fork head domain) UP00530A (Fork head domain) |
| Binding Sites: | GTAAACAA ATAAACAA ATTGTTTA GACGCGTC TAAACAAA AAAGCGTC ACCGCGTC AGACGCCA AGACGCTA AGGACGCG ATAGCGTC ATCGCGTC ATGGCGTC CCGCGTCC CGACGCTA GACGCCAA GACGCTAA GACGCTAC GGACGCTA TAGCGTCA |
| Publications: | Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A 110:12349-54 (2013). [Pubmed] |
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