DNA Binding Motif

Accessions: 4fth_AB (3D-footprint 20231221)
Names: Transcriptional regulator (NtrC family)
Organisms: Aquifex aeolicus, strain VF5
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of NtrC4 DNA-binding domain bound to double-stranded DNA
Length: 15
Consensus: TTGCAnnnnTGCAAA
Weblogo:
PSSM: P0 A C G T
01 5 5 5 81 T
02 0 0 0 96 T
03 0 0 96 0 G
04 0 96 0 0 C
05 67 11 7 11 A
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 5 7 5 79 T
11 0 0 96 0 G
12 0 96 0 0 C
13 84 0 5 7 A
14 96 0 0 0 A
15 67 11 5 13 A
Type: Heterodimer
Binding TFs: 4fth_A (Bacterial regulatory protein, Fis family)
4fth_B (Bacterial regulatory protein, Fis family)
Binding Sites: 4fth_C
4fth_D
Publications: Vidangos N.K, Heideker J, Lyubimov A, Lamers M, Huo Y, Pelton J.G, Ton J, Gralla J, Berger J, Wemmer D.E. DNA recognition by a σ(54) transcriptional activator from Aquifex aeolicus. Journal of molecular biology 426:3553-68 (2014). [Pubmed]

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